| 2021-02-09 19:00:00February 9, 2021 | Ottawa (24) vs Sandwich (29) | 24 - 29 | 2020/21 Girls Varsity Basketball | Sandwich |
| 2021-02-09 19:00:00February 9, 2021 | Sycamore (64) vs Rochelle (25) | 64 - 25 | 2020/21 Girls Varsity Basketball | Rochelle |
| 2021-02-09 19:00:00February 9, 2021 | Plano (32) vs Kaneland (53) | 32 - 53 | 2020/21 Girls Varsity Basketball | Kaneland |
| 2021-02-12 19:00:00February 12, 2021 | Sycamore (53) vs Ottawa (19) | 53 - 19 | 2020/21 Girls Varsity Basketball | Ottawa |
| 2021-02-12 19:00:00February 12, 2021 | Sandwich (43) vs Plano (14) | 43 - 14 | 2020/21 Girls Varsity Basketball | Plano |
| 2021-02-12 19:00:00February 12, 2021 | Rochelle vs LaSalle Peru | 19:00:007:00 pm | 2020/21 Girls Varsity Basketball | LaSalle Peru |
| 2021-02-12 19:00:00February 12, 2021 | Kaneland (64) vs Morris (27) | 64 - 27 | 2020/21 Girls Varsity Basketball | Morris |
| 2021-02-13 18:00:00February 13, 2021 | Ottawa (35) vs Plano (21) | 35 - 21 | 2020/21 Girls Varsity Basketball | Plano |
| 2021-02-13 18:00:00February 13, 2021 | LaSalle Peru vs Sycamore | 18:00:006:00 pm | 2020/21 Girls Varsity Basketball | Sycamore |
| 2021-02-13 18:00:00February 13, 2021 | Kaneland (32) vs Rochelle (37) OT | 32 - 37 | 2020/21 Girls Varsity Basketball | Rochelle |
| 2021-02-17 19:00:00February 17, 2021 | LaSalle Peru (41) vs Ottawa (42) | 41 - 42 | 2020/21 Girls Varsity Basketball | Ottawa |
| 2021-02-17 19:00:00February 17, 2021 | Kaneland (36) vs Sycamore (59) | 36 - 59 | 2020/21 Girls Varsity Basketball | Sycamore |
| 2021-02-17 19:00:00February 17, 2021 | Rochelle (34) vs Sandwich (42) | 34 - 42 | 2020/21 Girls Varsity Basketball | Sandwich |
| 2021-02-19 19:00:00February 19, 2021 | Morris vs Ottawa | 19:00:007:00 pm | 2020/21 Girls Varsity Basketball | Ottawa |
| 2021-02-19 19:00:00February 19, 2021 | LaSalle Peru (47) vs Kaneland (55) | 47 - 55 | 2020/21 Girls Varsity Basketball | Kaneland |
| 2021-02-19 19:00:00February 19, 2021 | Plano (19) vs Rochelle (51) | 19 - 51 | 2020/21 Girls Varsity Basketball | Rochelle |
| 2021-02-19 19:00:00February 19, 2021 | Sandwich (23) vs Sycamore (45) | 23 - 45 | 2020/21 Girls Varsity Basketball | Sycamore |
| 2021-02-22 19:00:00February 22, 2021 | Ottawa (45) vs Kaneland (51) | 45 - 51 | 2020/21 Girls Varsity Basketball | Kaneland |
| 2021-02-22 19:00:00February 22, 2021 | Rochelle (26) vs Morris (28) | 26 - 28 | 2020/21 Girls Varsity Basketball | Morris |
| 2021-02-22 19:00:00February 22, 2021 | Sandwich (49) vs LaSalle Peru (35) | 49 - 35 | 2020/21 Girls Varsity Basketball | LaSalle Peru |
| 2021-02-22 19:00:00February 22, 2021 | Sycamore (61) vs Plano (21) | 61 - 21 | 2020/21 Girls Varsity Basketball | Plano |
| 2021-02-24 19:00:00February 24, 2021 | Rochelle (27) vs Ottawa (32) | 27 - 32 | 2020/21 Girls Varsity Basketball | Ottawa |
| 2021-02-24 19:00:00February 24, 2021 | Sandwich (30) vs Kaneland (48) | 30 - 48 | 2020/21 Girls Varsity Basketball | Kaneland |
| 2021-02-24 19:00:00February 24, 2021 | Sycamore (61) vs Morris (5) | 61 - 5 | 2020/21 Girls Varsity Basketball | Morris |
| 2021-02-24 19:00:00February 24, 2021 | Plano (56) vs LaSalle Peru (65) | 56 - 65 | 2020/21 Girls Varsity Basketball | LaSalle Peru |
| 2021-02-26 19:00:00February 26, 2021 | Sandwich (34) vs Ottawa (31) | 34 - 31 | 2020/21 Girls Varsity Basketball | Ottawa |
| 2021-02-26 19:00:00February 26, 2021 | Rochelle (30) vs Sycamore (56) | 30 - 56 | 2020/21 Girls Varsity Basketball | Sycamore |
| 2021-02-26 19:00:00February 26, 2021 | Kaneland (62) vs Plano (37) | 62 - 37 | 2020/21 Girls Varsity Basketball | Plano |
| 2021-02-26 19:00:00February 26, 2021 | Morris (30) vs LaSalle Peru (44) | 30 - 44 | 2020/21 Girls Varsity Basketball | LaSalle Peru |
| 2021-02-27 13:00:00February 27, 2021 | LaSalle Peru (38) vs Morris (22) | 38 - 22 | 2020/21 Girls Varsity Basketball | Morris |
| 2021-03-01 19:00:00March 1, 2021 | Ottawa (16) vs Sycamore (37) | 16 - 37 | 2020/21 Girls Varsity Basketball | Sycamore |
| 2021-03-01 19:00:00March 1, 2021 | Plano (15) vs Sandwich (43) | 15 - 43 | 2020/21 Girls Varsity Basketball | Sandwich |
| 2021-03-01 19:00:00March 1, 2021 | LaSalle Peru (54) vs Rochelle (40) | 54 - 40 | 2020/21 Girls Varsity Basketball | Rochelle |
| 2021-03-01 19:00:00March 1, 2021 | Morris (10) vs Kaneland (48) | 10 - 48 | 2020/21 Girls Varsity Basketball | Kaneland |
| 2021-03-03 19:00:00March 3, 2021 | Plano (11) vs Ottawa (41) | 11 - 41 | 2020/21 Girls Varsity Basketball | Ottawa |
| 2021-03-03 19:00:00March 3, 2021 | Sycamore (65) vs LaSalle Peru (39) | 65 - 39 | 2020/21 Girls Varsity Basketball | LaSalle Peru |
| 2021-03-03 19:00:00March 3, 2021 | Sandwich (26) vs Morris (27) | 26 - 27 | 2020/21 Girls Varsity Basketball | Morris |
| 2021-03-03 19:00:00March 3, 2021 | Rochelle (38) vs Kaneland (52) | 38 - 52 | 2020/21 Girls Varsity Basketball | Kaneland |
| 2021-03-04 18:00:00March 4, 2021 | Morris (23) vs Sandwich (36) | 23 - 36 | 2020/21 Girls Varsity Basketball | Sandwich |
| 2021-03-05 19:00:00March 5, 2021 | Plano (42) vs Morris (34) | 42 - 34 | 2020/21 Girls Varsity Basketball | Morris |
| 2021-03-06 19:00:00March 6, 2021 | Ottawa (35) vs LaSalle Peru (47) | 35 - 47 | 2020/21 Girls Varsity Basketball | LaSalle Peru |
| 2021-03-06 19:00:00March 6, 2021 | Sycamore (61) vs Kaneland (43) | 61 - 43 | 2020/21 Girls Varsity Basketball | Kaneland |
| 2021-03-06 19:00:00March 6, 2021 | Sandwich (35) vs Rochelle (22) | 35 - 22 | 2020/21 Girls Varsity Basketball | Rochelle |
| 2021-03-08 19:00:00March 8, 2021 | Ottawa (35) vs Morris (22) | 35 - 22 | 2020/21 Girls Varsity Basketball | Morris |
| 2021-03-08 19:00:00March 8, 2021 | Kaneland vs LaSalle Peru | 19:00:007:00 pm | 2020/21 Girls Varsity Basketball | LaSalle Peru |
| 2021-03-08 19:00:00March 8, 2021 | Sycamore (45) vs Sandwich (40) | 45 - 40 | 2020/21 Girls Varsity Basketball | Sandwich |
| 2021-03-09 19:00:00March 9, 2021 | Rochelle (39) vs Plano (48) | 39 - 48 | 2020/21 Girls Varsity Basketball | Plano |
| 2021-03-10 19:00:00March 10, 2021 | Kaneland (24) vs Ottawa (43) | 24 - 43 | 2020/21 Girls Varsity Basketball | Ottawa |
| 2021-03-10 19:00:00March 10, 2021 | Morris (29) vs Rochelle (40) | 29 - 40 | 2020/21 Girls Varsity Basketball | Rochelle |
| 2021-03-10 19:00:00March 10, 2021 | LaSalle Peru vs Sandwich | 19:00:007:00 pm | 2020/21 Girls Varsity Basketball | Sandwich |
| 2021-03-10 19:00:00March 10, 2021 | Plano (38) vs Sycamore (67) | 38 - 67 | 2020/21 Girls Varsity Basketball | Sycamore |
| 2021-03-12 19:00:00March 12, 2021 | Ottawa (53) vs Rochelle (44) | 53 - 44 | 2020/21 Girls Varsity Basketball | Rochelle |
| 2021-03-12 19:00:00March 12, 2021 | Kaneland (47) vs Sandwich (34) | 47 - 37 | 2020/21 Girls Varsity Basketball | Sandwich |
| 2021-03-12 19:00:00March 12, 2021 | Morris (19) vs Sycamore (53) | 19 - 53 | 2020/21 Girls Varsity Basketball | Sycamore |
| 2021-03-12 19:00:00March 12, 2021 | LaSalle Peru vs Plano | 19:00:007:00 pm | 2020/21 Girls Varsity Basketball | Plano |
| 2021-03-13 15:00:00March 13, 2021 | Morris (37) vs Plano (51) | 37 - 51 | 2020/21 Girls Varsity Basketball | Plano |
